Thursday, 9 June 2022

Businesses in Thailand Eager to Invest in the Countrys New Legal Cannabis Industry

Free Malaysia Today reports that cannabis in both recreational and industrial form will be removed from Thailand’s Category 5 narcotics designation on June 9th, citing a ruling from the Thai Food and Drug Administration. Cultivators wishing to conduct legal cannabis business will be able to register via the Pluk Kan mobile application.

According to the Global Cannabis Report the legal cannabis market is valued at US$100 billion globally.

Thailand’s cannabis industry is generating widespread interest and has already attracted 1.2 million baht worth of investment. There is a rush to exploit the nascent cannabis market in Thailand now that the plant will be decriminalized. The excitement among existing corporate players is palpable as investors prepare to jump in.

Thailand now stands as the first Southeast Asian nation to legalize cannabis and its industrial cousin hemp.

Thailand’s largest conglomerate, Charoen Pokphand Foods (CPF), is getting in on the action, forming a joint venture between their food and beverage wing and Gunkul Engineering, a renewable energy developer, to begin production of CBD-infused food and beverages in addition to industrial hemp production. The resulting products will be marketed via CPF’s retail outlets.

“CPF takes an interest in hemp as a new economic crop that can be turned into value-added food and beverages in light of growing demand, both domestically and internationally,” said Prasit Boondoungprasert, the CEO of the company.

Thailand allowed the cultivation of cannabis to be used for medical applications in 2019 and sanctioned its use in drinks and foods last year. Since that time it has been incorporated into both western and traditional Thai foods.

All eyes are on other Southeast Asian countries to see which nation might be the next to end the prohibition of cannabis and start enjoying the economic benefits of legalization.

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Emerald Cup Deepens its Committment to Legacy Small farms and Regenerative Sungrown Cannabis

When the Emerald Cup (www.theemeraldcup.com) announced an expansion into the Southern California market, some critics wondered if the 18-year tradition had lost its way or forgotten its roots. On the contrary, the road to the 2022 Emerald Cup Awards brought a caravan of the finest cannabis cultivators from the Emerald Triangle on a SoCal tour, promoting clean, pure sungrown cannabis and the folks who grow it to the world’s largest marijuana marketplace.

Emerald Cup Community

Since 2004, the Emerald Cup has honored these outdoor farmers with an annual competition and celebration. In contrast, since 2016 the state of California has created an unsustainable burden of cannabis regulation and taxation that presses down harder the smaller your operation is. This has led to the loss of legacy family farms and, in some cases, the loss of life as some farmers could not bear the emotional burden that came along with the financial one. 

Knowing that many mom n’ pop craft cannabis farms might not be able to muster the resources to represent themselves at the Emerald Cup last year, Cup co-Founders Tim and Taylor Blake formed an advisory council to create the Emerald Cup Small Farms Initiative.

The Emerald Cup recognizes that their heritage, small-batch craft cannabis cultivators in Northern California are facing an existential crisis resulting from a combination of taxation, licensing, and market conditions. In partnership with the Origins Council, a statewide advocacy organization representing licensed small farmers in legacy producing regions across California, the Emerald Cup launched the Emerald Cup Small Farms Initiative, which is Chaired by Michael Katz, the Executive Director of the Mendocino Cannabis Alliance (MCA)

Through the Emerald Cup Small Farm Initiative, the organization provided complimentary vending and competition opportunities to small cannabis farmers at this year’s Hall of Flowers (HOF) in Palm Springs. The program accepted submissions from small farmers of 10,000 sq ft of canopy or less with sustainable cultivation practices to help support their efforts in accessing the retail market.  

Wild Land Farms

Widely recognized as the top B2C (Business-to-Consumer) and B2B (Business-to-Business) gatherings in the cannabis space, the Emerald Cup and Hall of Flowers, in partnership with the Origins Council, and the Mendocino Cannabis Alliance, provided complimentary booth space at Hall of Flowers to four legacy craft cannabis farms; Flying Tiger Farm, Perrin Family Farm, Tall Tree Society, and WildLand Cannabis. Michael Katz from MCA explains the significance of the collaboration between HOF, the Emerald Cup, and the Small Farms Initiative by saying “It has been incredible to see the love and support for the legacy cannabis cultivation community translating into concrete opportunities for market access from The Emerald Cup and Hall of Flowers.  Through the Small Farms Initiative, we hope to continue inspiring and developing more of these direct connections between small farmers and the people who care about their cannabis!”

Hot on the heels of Hall of Flowers, the Emerald Cup was invited to attend the private grand opening of The Woods dispensary in West Hollywood on May 13th, 2022 which marked the start of a budding relationship between retail cannabis supporting small farms.

Carrying the Emerald Cup Small Farms Initiative Spirit, The Woods (www.thewoodsweho.com) founded by actor and outspoken advocate, Woody Harrelson, this year’s recipient of the 2022 Willie Nelson Lifetime Achievement Award at the 18th Annual Emerald Cup Awards. The Woods, which is located on Santa Monica Boulevard in the heart of WeHo, has dedicated ample shelf space to legacy, sungrown, craft cannabis farms like Huckleberry Hill Farms, Happy Day Farms, Arcanna Flowers, Moon Made Farms, and more. The Woods Co-Founder, Devon Wheeler added “We strive to be the vehicle that drives awareness and appreciation towards sungrown, craft cannabis – ensuring the legacy of California heirloom doesn’t get washed out by corporate cannabis.”


The Woods – 8271 Santa Monica Blvd, West Hollywood, CA 90046  –  Photo Credit: Stephanie Keenan

The road to the Small Farms Initiative began in Santa Rosa in December of 2021, and six months and 420 miles later it culminated on May 14th, 2022 at the Ricardo Montalban Theatre in Hollywood.

Over 700 entries were submitted in the world’s largest and most diverse cannabis competition, filling over 50 different categories and creating a daunting challenge for the 90+ Emerald Cup Judges tasked with sampling and ranking it all. Working with cannabis advocacy partners like the Origins Council, Mendocino Cannabis Alliance, and others, the Cup offered heavily discounted entry fees to 21 farms that met the strict criteria associated with these highly reputable groups. Additionally, the Cup offered complimentary entry to 10 small farms to compete in this year’s judging competition that otherwise would not have been able to participate. Several of these small farms wound up bringing home awards, including 1st place wins by Emerald Spirit Botanicals, Lit House, Sovereign, Sunrise Mountain Farm, Lost Paradise Organics, Sol Spirit Farms, Moon Valley Farms, Rebel Grown, and Flower Power. These wins reflect how important programs like this are to helping provide access to small farms growing some of the best cannabis in the world but who are severely challenged by the challenges in the California market.

In fact, the winner of the Sungrown Flower category, Lemon Sponge Cake by Farmer and the Felon, also won ‘Best in Show’, beating out the top entries in Greenhouse, Mixed Light, and Indoor along the way. There is just something about sungrown cannabis and the Emerald Cup continues to advocate for the farms that grow it well and grow it in a regenerative, earth-friendly manner.

“It was a tremendous source of validation to see so many small farmers in the spotlight at the Emerald Cup Awards ceremony, out at Hall of Flowers, and at the gathering at the private opening of The Woods as well,” says Tim Blake. “After evangelizing to the community since cannabis was legalized about how critical it was for smaller farmers and brands to connect with the cannabis market in Southern California, to see so many lights go on in the minds of all the folks who made the trek to L.A. was incredibly appreciated.”

Before and after the Emerald Cup Awards show, friendly farmers could be seen strolling on the iconic Hollywood Walk of Fame, stars in their own right, shining and growing cannabis under the sun. There truly was a vibe in the air that a vital connection had been made there that weekend.

Media needing to connect with The Emerald Cup and Emerald Cup 2022 Awards Show, or to speak with founder Tim Blake regarding this announcement, please reach out to Kenneth Loo, Chapter 2 at ken@chapter2agency.com.

For more information and to get updates on upcoming events follow the Emerald Cup @theemeraldcup

To Shop Flying Tiger Farm, Perrin Family Farm, Tall Tree Society, and WildLand Cannabis please visit MendocinoCannabis.shop

Hi-Res images of the 2022 Emerald Cup Awards

Photo Credit: Emerald Cup

ABOUT THE EMERALD CUP:

Landing in Hollywood in 2022, Emerald Cup is now the world’s premier virtual cannabis destination and iconic live event. While advancing the concept of sustainable, sun-grown farming, the 17-year-old organization’s reputation is firmly solidified as the largest, most-respected cannabis competition in the world. As a group, The Emerald Cup prides itself in bringing together the leading experts in the cannabis industry to educate and inspire our fellow farmers, patients, and patrons each year. A community celebration that has grown to become a global movement honoring the year’s finest, organic, sun-grown, cannabis harvest as well as the finest cannabis products available. The Cup has stood as a celebration of excellence and over the years has seen founder Tim Blake recognized as a guardian of the industry. (www.theemeraldcup.com)

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How Strain Genetics Influence THC/CBD Ratios

It’s relatively common knowledge that different cannabis strains produce different effects.
Often this can be attributed to other cannabis constituents such as terpenes, but the differences in effects are primarily due to variations in the THC/CBD ratio. The relative concentration of THC and CBD is chemotype dependent.

Yet, what is a chemotype? According to experts, a chemotype is a subgroup within a microorganism or plant species. [1] Different chemotypes have distinct chemical profile because of the minuscule genetic changes allowing a cannabis plant to produce a peculiar chemical composition. [2] Our article will discuss these chemotypes and how strain genetics influence THC/CBD ratios.

What is the THC/CBD ratio (1:1)?

In most instances, the THC/CBD ratio (1:1) refers to a cannabis product containing an equal amount of THC and CBD. According to various studies on the topic, many people prefer this THC/CBD ratio because the effects are considered more tolerable. Ultimately, this is because CBD is believed to dampen the psychoactivity and side effects of THC to a certain extent.

How do the strain genetics influence THC/CBD ratios?

Let’s unpack how these strain genetics can influence the THC/CBD ratio. As is the case with most animals and plants, cannabis plants inherit two gene copies, but unlike other plants, the enzymes that turn cannabigerolic acid (CBGA) into tetrahydrocannabinolic acid (THCA) or cannabidiolic acid (CBDA) are ciphered by two uniquely different versions of the same gene.

Due to this, a cannabis plant has two copies of the gene, so that’s why there are three possibilities or three chemotypes. A cannabis plant can have two copies of a gene in one enzyme (E1), it can have one copy of each of the genes (E1&E2), or it can have two copies of a gene in another enzyme (E2). The three THC/CBD ratio strain classifications are discussed under the next heading. [2]

These are the three chemotypes of cannabis

Every cannabis strain is unique, but by knowing the general chemotype classification, a consumer can know what effect they should expect from a strain. A perfect example is that the CBD dominant (chemotype III) strains won’t be as psychoactive compared to THC dominant strains (chemotype I).

  • Chemotype I (hemp): This chemotype is THC dominant which means it has low levels of CBD but high levels of THC. When a strain inherits two copies of the E2 gene, this occurs. It’s believed that most commercial strains belong to this category. A few examples of these strains include Girl Scout Cookies and Blue Dream.
  • Chemotype II: This chemotype is balanced with moderate levels of CBD and THC. When a strain gets a copy in each of the E1 and E2 genes, this occurs. Popular examples of balanced strains include Cannatonic and Harlequin.
  • Chemotype III: This chemotype is CBD dominant with low THC levels but high levels of CBD. When a strain receives two copies of the gene that makes E1, this chemotype occurs. Charlotte’s Web is one of the most famous strains in this category.

Why are THC/CBD ratios important?

It is important to know the precise THC/CBD ratio because, depending on the type of product bought, there will be a different biological response of the body depending on the particular strain consumed. For example, a strain with more CBD will produce a clear-headed non-psychoactive effect which helps ease the mind and nerves.

In contrast, a THC dominant ratio produces a significantly higher psychoactive effect, with a pacifying impact on a person’s body or an energizing and euphoric effect depending on the variety, thus the different chemical composition.

References:

[1] Pacifico, D. et al. Genetics and Marker-assisted Selection of the Chemotype in Cannabis sativa L. Molecular Breeding; (2006).17(3), 257-268. doi: 10.1007/s11032-005-5681-x   [Journal impact factor = 3.26] [Times cited = 111][2] Campbell, L. et al. (2020). Cannabinoid Inheritance Relies on Complex Genetic Architecture. Cannabis And Cannabinoid Research, 5(1), 105-116. doi: 10.1089/can.2018.0015 [Journal impact factor = 4.30] [Times cited = 4]

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What Makes A Cannabinoid Potent

A 2010 study that tested 46,211 samples of cannabis for potency found an upward trend in strength between the years 1993-2008. [1] During that time period, the average THC percentage went from a mean of 3.4% to 8%, with some samples reaching as high as 29.3% strength. As cannabis becomes more regulated, measuring its potency, thus its THC content, becomes increasingly important in order to evaluate the risks and rewards of increased usage.

How we respond to various cannabinoids

Cannabis primarily bonds to two cannabinoid receptors in the human body called CB1 and CB2 receptors. [2] THC, the primary psychoactive cannabinoid, primarily binds to CB1 receptors while CBD, the second most common cannabinoid, can interact with both receptors. Scientists have found as many as 120 other cannabinoids present in cannabis in various concentrations, leading to possible variations in cannabis potency. [3]

How minor cannabinoids can affect potency

Cannabinoids vary based on their chemical structures. As more cannabinoids are isolated and identified, it is possible to study how each compound may produce various effects. [4] One example: varinic cannabinoids, don’t interact well with CB1 receptors as they are composed of less than 2 carbon atoms. [5] Current research suggests varinic cannabinoids may be useful in treatment of people affected by autism. Another: cannabitrol  (CBT) has shown promise in the treatment of breast cancer: this cannabinoids with 8-9 carbon atoms tend to bind more to estrogen receptors than cannabinoid receptors. [6]

The risks of high-potency cannabis

While many of these newly discovered cannabinoids show therapeutic potential for a variety of treatments, there are also potential risks associated with higher potency cannabis. Addiction specialists have compared it to the strengthening of alcohol or tobacco, claiming, “The more potent a drug is, the stronger the possibility of addiction and the more likely the person will continue to purchase and use the product.” [7] High potency cannabis also may increase the risk of psychosis or have a “detrimental effect on cognitive function.” [8] With this in mind, it may prove to be productive to spend more time investigating minor cannabinoids as an alternative to high potency cannabis.

 

References:

[1] Mehmedic, Z. et al. Potency Trends of Δ9-THC and Other Cannabinoids in Confiscated Cannabis Preparations from 1993 to 2008*. Journal of Forensic Sciences; (2010);  55(5), 1209–1217. https://doi.org/10.1111/j.1556-4029.2010.01441.[2] Reggio, P. Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown. Current Medicinal Chemistry; (2010); 17(14), 1468–1486. https://doi.org/10.2174/092986710790980005 [Journal impact factor = 4.184 ] [Times cited = 184][3] Walsh, K. B. et al. Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses. Frontiers in Pharmacology; (2021); 12. https://doi.org/10.3389/fphar.2021.777804 [Journal impact factor = 4.400 ] [Times cited = 4][4] Radwan, M. M. et al. Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-PotencyCannabis sativa. Journal of Natural Products; (2015); 78(6), 1271–1276. https://doi.org/10.1021/acs.jnatprod.5b00065 [Journal impact factor = 4.050] [Times cited = 122]

 

[5] Navarro, G. et al. Pharmacological data of cannabidiol- and cannabigerol-type phytocannabinoids acting on cannabinoid CB1, CB2 and CB1/CB2 heteromer receptors. Pharmacological Research; (2020); 159, 104940. https://doi.org/10.1016/j.phrs.2020.104940 [Journal impact factor = 7.65] [Times cited = 32][6] Carbone, M. et al. Chemical characterisation of oxidative degradation products of Δ9-THC. Tetrahedron; (2010); 66(49), 9497–9501. https://doi.org/10.1016/j.tet.2010.10.025 [Journal impact factor = 2.475] [Times cited = 32][7] Stuyt, E. et al. The Problem with the current high Potency THC marijuana from the Perspective of an Addiction Psychiatrist. Missouri Medicine; (2018); 115(6), 482–486. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312155/pdf/ms115_p0482.pdf [Times cited = 51][8] Murray, R. M. et al. Traditional marijuana, high-potency cannabis and synthetic cannabinoids: increasing risk for psychosis. World Psychiatry; (2016);  15(3), 195–204. https://ift.tt/JbCTqpX [Journal impact factor = 49.548] [Times cited = 226]

 

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CBD and the Heart Rate

With the cardiovascular system being one of the most complex mechanisms in our body, and heart problems being the leading cause of death, claims about cardiovascular benefits shouldn’t be made lightly. This is particularly true when it comes to cannabinoids such as cannabidiol (CBD), which are still in very infant stages of their scientific and medicinal research. Nevertheless, there’s a reason to believe that CBD can positively, be it mildly, affect your heart rate, both directly and indirectly.

Indirect

Stress is infamous for being the heart’s arch-nemesis. CBD, on the other hand, became famous especially as stress antidote, one that comes without any serious adverse effects. By the logic of “the enemy of my enemy is my friend,” CBD is a great ally in the fight against heart problems, even if it operates relatively indirectly.
Speaking of logic and combatants, there’s another side note worth mentioning: tetrahydrocannabinol (THC), the major psychotropic cannabinoid of cannabis, is known for increasing the heart rate potentially causing arrythmia in predisposed people.
CBD is THC’s counterpoint, softening its effects.

Direct

Transient receptor potential cation channel subfamily V, member 1 (TRPV1) is one of a group of channels whose physiological functions play an important role in the cardiovascular system and its diseases.
CBD works as a desensitizer of TRPV1 and, in doing so, it produces a mildly calming effect on the heart and reduces metabolic rates of heart muscles. [1]

Interestingly in a crossover, placebo-controlled, double-blind study on nine healthy volunteers, a single dose of 600 mg of CBD reduced blood pressure while increasing heart rate, especially during the first hour after administration. This was largely attributed to the high dosage. [2]

Perhaps more noteworthy is that CBD’s ability to restore balance may translate into a decreased heart rate variability. Spikes in the heart rate because of stressors can be detrimental, so this can have major implications.

For instance, a study on rats, exposed to acute restraint stress, found CBD to attenuate “acute autonomic responses to stress and its delayed emotional consequences by facilitating 5-HT1A receptor-mediated neurotransmission.” [3]

Of course, studies on rats don’t hold the same weight as those on humans. Research from the latter type on CBD’s influence on heart rate are scarce. Nevertheless, there is one study of 2021, concluding that “acute CBD ingestion may have a modest influence on autonomic regulation of heart.” [4]

Finally, it’s worth mentioning that CBD has displayed some ability to reduce blockages and plaques in the cardiovascular system, thus improving blood flow [5].

The Bottom Line

There are some grounds  to believe that CBD can benefit the heart rate and the cardiovascular system as a whole, especially considering its negligeable risks of side effects. CBD can be a valuable adjunct therapy that, coordinated with a doctor, can be a potential preventative measure promoting health and the overall wellbeing.

References:

[1] Alfulaij et al, Cannabinoids, the Heart of the Matter, Journal of the American Heart Association, Vol. 7, No. 14; https://doi.org/10.1161/JAHA.118.009099 [Journal Impact Factor = 5.501] [ Times cited = 33][2] Jadoon et al, A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study, JCI Insight. 2017 Jun 15; 2(12); doi: 10.1172/jci.insight.93760 [Journal Impact Factor = 8.315] [Times Cited = 97][3] Resstel et al, 5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats, 24 December 2008, British Journal of Pharmacology, Volume 156, Issue 1; doi: 10.1111/j.1476-5381.2008.00046.x [Journal Impact Factor = 8.739] [Times Cited = 270][4] Williams et al, Comparison of Five Oral Cannabidiol Preparations in Adult Humans: Pharmacokinetics, Body Composition, and Heart Rate Variability, Pharmaceuticals 202114(1),35, 6; doi: 10.3390/ph14010035 [Journal Impact Factor = 5.677] [Times Cited = 8]

 

[5] Gonca and Darici, The Effect of Cannabidiol on Ischemia/Reperfusion-Induced Ventricular Arrhythmias: The Role of Adenosine A1 Receptors, Journal of Cardiovascular Pharmacology and Therapeutics; doi: 10.1177/1074248414532013 [Journal Impact Factor = 2.457] [Times Cited = 63]

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Wednesday, 8 June 2022

CBD hits roadblocks for use as food in Europe, for reasons similar to US

The European agency in charge of food safety has announced a pause on evaluations for cannabidiol (CBD) as food while it gathers more data on safety.

The European Commission, one of the governing bodies of the European Union, had previously established that CBD can be considered a “novel food” as long as it meets the relevant criteria. In the EU, novel food regulations apply to any food without a significant history as part of the human diet before the regulations were put in place in 1997. CBD is a non-intoxicating compound that can be extracted from cannabis plants including hemp, and does not have a known history as food in the EU.

After 19 applicants sought approval for CBD as a novel food, with more applications expected, the European Food Safety Authority said it wouldn’t be approving any of them until it had more information.

“[I]t has become clear that there are knowledge gaps that need to be addressed before a conclusion on the safety of CBD can be reached,” the EFSA said in a statement.

Within the EFSA, a group of experts reviews such applications: the Panel on Nutrition, Novel Foods and Food Allergens (NDA).

The chair of the NDA panel, Prof. Dominique Turck, said, “We have identified several hazards related to CBD intake and determined that the many data gaps on these health effects need filling before these evaluations can go ahead. It is important to stress at this point that we have not concluded that CBD is unsafe as food.”

“It is important to stress at this point that we have not concluded that CBD is unsafe as food.”

— Professor Dominique Turck, Chair of the Panel on Nutrition, Novel Foods and Food Allergens

Specifically, the NDA hopes to gather data on how CBD affects the liver, gastrointestinal tract, endocrine system, reproductive system, nervous system and psychological well-being.

“Stopping the clock on a novel food assessment is not unusual when information is missing,” said Ana Afonso, Head of Nutrition and Food Innovation at EFSA. “It’s the responsibility of applicants to fill data gaps. We are engaging with them to explain how the additional information can be provided to help address the uncertainties.”

“Stopping the clock on a novel food assessment is not unusual when information is missing.”

— Ana Afonso, Head of Nutrition and Food Innovation at European Food Safety Authority

In US, FDA Has Also Been Slow to Approve CBD as Food

Getting federal approval for CBD and other cannabinoids to be used in food and dietary supplements has been difficult in the United States too, for similar reasons.

Despite repeated requests from federal lawmakers and the food industry, the US Food and Drug Administration (FDA) has yet to build a regulatory framework for CBD. The agency maintains it needs time to study potential health risks before creating regulations.

“Clear answers to many important questions are still lacking,” the acting chair of the FDA’s cannabis-product committee said last November, “such as what adverse reactions may be associated with CBD from hemp-derived products and what risks are associated with the longterm use of these products.”

Meanwhile, sales of hemp extracts continue in a regulatory gray area with little oversight on safety testing or labeling.

In April, US House Representative James Comer (R-KY) requested a committee-level hearing with the FDA to address its failure to establish regulations for the sale of hemp-derived extracts including CBD.

“Across the United States, inauthentic products are sold under the likeness of legal hemp but are improperly labeled, contaminated with harmful chemicals, and marketed to children,” Comer wrote. “We must hear directly from the FDA to ensure the agency has a plan to institute a regulatory solution that can effectively monitor the sale of hemp products and protect the health of children.”

In his letter, Comer noted that in legalizing hemp with the 2018 Farm Bill, Congress had tasked the FDA with oversight of consumable hemp products.

The head of the FDA has since agreed with critics who say the agency has done little to regulate CBD products since hemp was legalized in 2018, but also said the FDA would need greater regulatory authority to build enforceable rules for hemp extracts and derivatives.


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Tuesday, 7 June 2022

Letters to Rev Soil Structure for Growing Cannabis

When it comes to soil structure for growing cannabis, we can all easily see some of the big differences between growing in the ground or in containers. Today’s article checks out a few of your issues of late I have read about, regarding soil structure in general.

Alright then earthlings, let’s rock and/or roll with today’s “Letters” to Rev…

Soil Structure, Question #1: Pumice?

FROM: John Q.

“Hey ya Rev. I don’t have much space to work with beyond my actual gardening spaces indoors. I’m basically bankrupt on storage space. I can keep one aeration amendment on hand in a fairly large size. I have kind of landed on pumice. Before I pull the trigger on this, I just wanted to get your input. Thanks, Rev, I can’t wait to get the new book!”

Rev’s Answer to Q1

Yo John. Thanks a ton for the support man, writing a book is pretty insane, workwise; LoL! Here’s the dealio, according to me… If I were you, knowing what I know, I would use perlite as my main amendment to aerate container soil, for a few reasons. That being said, I love-love-love pumice, and I use it along with perlite, and vermiculite too. Pumice, along with all its other outstanding qualities, also inhibits fungal growth—which is nice for cannabis—to a point.

Pumice is Awesome for Soil Structure and Especially Bacterial Soil Life
Pumice is Awesome for Soil Structure and Especially Bacterial Soil Life

Cannabis prefers bacterial dominant soil types, but there needs to be a balance between fungi and bacteria. I feel that using too much pumice in a soil mix may have negative effects on some of the good fungi in the mix. Like, say, the mycorrhizal fungus. I do use approximately ½ cup of pumice per about 4-cubic feet of soil (24-gallons) when I recycle my soil. If I were you, I would find a way to store a little pumice and more perlite. But perlite would be my sole choice.

Having a little vermiculite around is also a good thing for special situations, like sprouting, and planting freshly rooted clones. I feel ya regarding your space issues, I have grown in many different environments over the decades and a few of those were extremely space challenged. Perlite is also so lightweight, I used to just use a piece of duct tape to hang a 4-cubic foot bag from rafters. Pumice has more weight to it, it’s way heavier, and if it gets wet, it’s super heavy.

Soil Structure, Question #2: Using Coir Heavy Soil?

FROM: Tom M.

“I have started using a very coconut coir heavy soil mix as my living soil. Everything started out fantastic, but now I have problems left and right. Of course, these problems begin once I am three weeks into flowering. My plants all have a yellowish look on the top several nodes of leaves. I thought this was a pH issue so I used a little pH down and things became much worse. Please help Rev! Thank you.”

Rev’s Answer to Q2

I mean no insult when I say that you sound like a new grower. There are a lot of “rules” and physical laws you need to have a bit of a grip on; when growing indoors especially. Allow me to bring you up to speed on a couple of serious things I believe you have overlooked here…

First and foremost, if you are ever using coir as part or most of your soil mix, the coir MUST BE FULLY RINSED/FLUSHED! This is not a rule you can just dismiss. Coir carries a ton of great mineral salts, and uber tons of potassium is one of them. Unfortunately, these levels are so high as to be actually toxic to the plants. Yup… So, if you didn’t flush your coir, you’re boned and that’s it. Most growers that use coir in their mixes in greater amounts also use bottled organic nutrient liquids. The super-low pH of the organic nutrients counters the coir’s ability to raise the pH way up with super-salts. But they still rinse the coir first.

In Containers Perlite is Usually the Best Choice for Soil Structure Enhancement
In Containers Perlite is Usually the Best Choice for Soil Structure Enhancement

Another aspect here is how coir starts out as an excellent anti-compaction/aerating amendment for your containers’ soil. However, within a few weeks the coir is broken down and no longer has its anti-compaction qualities, and actually the coir sort of fuses together during decomp making it the opposite of an aerating amendment. Without another soil structure enhancing amendment anaerobic conditions are primed to happen, and this is what I would say is likely also happening to you.

Soil Structure, Question #3: Can I Make Just Vermiculite Work?

FROM: Johnny B.

“Greetings Rev. I have a situation where I can source vermiculite up the ass, but I have no options for perlite. I can’t really do online stuff so I have to rely on local suppliers. The vermiculite is agricultural grade and I can get 4 cu. ft. bags for a good deal. Can I just use vermiculite as my only amendment to help with aeration in my containers? Thanks for everything you do Rev.”

Rev’s Answer to Q3

Hey Johnny, greetings. The short answer is, yup, you sure can. But this will cause you to have to pay EXTRA attention to your watering habits very closely, you dig? Because as you likely know vermiculite can hold a shit-ton of water. More than soil can per volume, like 30x more at least. So, there’s that. You will be watering less often with some vermiculite in your soil. I would recommend a target of about 10% to 15% of your overall soil mix being vermiculite.

Vermiculite is a Fine Soil Structure Enhancement That Absorbs a Ton of Water
Vermiculite is a Fine Soil Structure Enhancement That Absorbs a Ton of Water

Vermiculite is actually very awesome stuffs. It (like pumice and perlite) has a pH of just about neutral 7.0 which is very bacterial friendly indeed. The vermiculite stores not only a lot of extra water but stores nutrients as well (like pumice). Vermiculite is super light like perlite, but unlike perlite which holds a little water on its exterior in nooks and crannies, vermiculite absorbs water. Once waterlogged vermiculite will be fairly heavy—duh—while perlite stays light.

Afterword

Well, my esteemed homeskillets, that’s about it for today. I just want to say, regarding coir as a soil amendment. I no longer use it, and while it is fine in special situations you don’t really ever need it all. If you have some kind of desire to use it don’t even think about using it if it isn’t fully rinsed or flushed. Several years ago, you could still buy rinsed coir that had been left out in the rain for days before drying and packaging. Otherwise, you need to flush it out yourself. Also please, never ever use pH-Up or pH-down products on living soil. Ugh.

These days my main aeration and anti-compaction amendment is perlite, but there are also small levels of vermiculite and pumice as well. Perlite and pumice recycle extremely well and so less is added over time. Vermiculite kind of fully breaks down more rapidly than the other two, but it still hangs in for a while first—like 2 recycles for vermiculite, while perlite and pumice stay very well formed for many recycles.

Candyman Skunk Seeds—Say What
Candyman Skunk Seeds—Say What?

Back to working on the new book for me, whew. Swing by Kingdom Organic Seeds  and grab some of the latest: La Smush, Black SEA, and Candyman Skunk! Candyman Skunk will be available within a week or so of this publishing date. Get a copy of my latest TLO 2nd Edition book and learn the ways of the all-natural container grower Grasshopper. L8r G8rs…

  • REv
    ?

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Everything is Possible With POSIBL Cannabis: Grown Under the Sun

Ever since I traveled to Holland as a boy, and saw how they grew flowers for the world, I was inspired by the concept of Dutch Greenhouses. Enter the current day — the concept of growing cannabis under the sun is more than just a possibility, it’s the reason companies like POSIBL exist in the first place. POSIBL is the cannabis farm of the future and engine for several of California’s leading brands. POSIBL is redefining what it means to produce the highest quality cannabis. Leveraging a state-of-art system that uses less to do more, POSIBL brings the best greenhouse technology and expertise from traditional agriculture into cannabis and pairs it with the best possible genetics to produce the perfect flower — grown in an ethical, sustainable, free of pesticide and cost-efficient way, year-round. The technology is as old as the greenhouses that I saw in Holland back in the 1970s. Growing cannabis in a greenhouse, using a mixed light supplemental system, is more than just intriguing, it’s the kind of cannabis that really gets me stoned. Not that I’ve tried the POSIBL brands yet, maybe I’ll have the chance when I’m out west again. It’s like that for me, making a laundry list of haves and have-nots. That is the question. And now, without further ado, may I please introduce Jesus Burrola, Chief Executive Officer of POSIBL. Cheers. WB

Photo Credit: Ben Lalande

WB: Please tell me about yourself, what do you do for work? Where are you from? Live now?  What did you want to be when you grew up?  

Jesus Burrola: My name is Jesus Burrola, and I am the CEO of POSIBL, a grower and co-packer out of Salinas, CA. We operate a 12-acre mixed light greenhouse, and power 15 large brands in CA. I was born and raised in Mexico and lived there until I was 18. I grew up around distribution, since my father owned a distribution business, and was interested in how to streamline logistics and operations. This led me to pursue a career in supply chain management, and I ended up working for the largest building materials distributor in North America for 15 years prior to joining POSIBL. The desire to help be a part of this new industry and help shape its direction of it and help destigmatize the plant led me to join POSIBL two years ago.

WB: What are you working on right now? Do you have a six and twelve-month goal? What makes your company different from its peers?

Jesus Burrola: We have 2 big priorities.

1) The launch of our first B2C brand Humo, which is focused on representing the Latino community. Being Latinos in the space, we felt there was no brand in existence that really catered to our community, which makes up over 30% of the California population and a huge portion of the participants in the industry. We see this as an opportunity to help reduce the stigma of cannabis in our community.

Photo Credit: Ben Lalande

2) The buildout of our new state-of-the-art greenhouses and processing facility. For the past few years, we have been working on getting a high-tech greenhouse project designed and permitted for expansion. We are, thankfully now, at the point where we kicked off construction. This project will take 14-18 months to be fully built out, but once it’s done it will be one of the most sustainable and tech-forward cannabis projects in the state.

WB: What obstacles stand in your way currently, and how do you anticipate removing them? Do you have a mentor or teacher who is valuable in your path? 

Jesus Burrola: The largest challenge is the broken regulations and taxes that exist in California for cannabis operators. These in turn have created a very difficult market, where the heavy tax burden and added costs of the regulations make it extremely difficult to transition consumers to the legal market and have led to extremely low pricing for growers.

WB: Greenhouse, indoor or outdoor grown cannabis? Favorite strain right now? When you enjoy cannabis, do you have a favorite food that you prepare? What about your favorite restaurant? 

Jesus Burrola: I am biased, but I would have to say greenhouse. I feel greenhouses with supplemental light are the best of all worlds, since you can incorporate the full spectrum of the sun and natural elements, but at the same time control the environment to give the ideal conditions for the plant to thrive and produce year-round. Sustainability is also important to us, and growing in a greenhouse environment allows us to reduce our carbon footprint.

My favorite strain right now has to be the Limonada. It is an energetic sativa with a citrus and sweet terpene profile.

To me, there is no better meal than authentic carne asada tacos. Being from Sonora, we take big pride in our claim to having Mexico’s best carne asada tacos. There is not a trip or visitor that doesn’t involve bringing freshly made tortillas to pair with some nice ribeye tacos and a cold beer.

WB: What is your passion? 

Jesus Burrola: Apart from my family, I would say my passion is learning. I am naturally curious and coming into cannabis from the grower side has been an incredible experience. Cannabis is a fascinating plant. I get to work with a team that is extremely knowledgeable and passionate about the plant, and I learn new things every day. I am extremely grateful to be able to work with such a great group of people that truly care about growing the best possible flower.

Feature Photo Credit: Ben Lalande

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Deep Dive into BEED Aengus Cawley Cannabis and Five Questions

Real cannabis imbibing intellects are the ones who dispel the notion that all cannabis smokers are still living in their parent’s homes, having failed to apply themselves in life. Nothing could be further than the truth. The popular culture paints cannabis smokers as unable to do anything but do bong hits all day. This is unfortunate, but a stark reality in many places in the world, especially in places like New Jersey, where I grew up. The very fact that I’ve used cannabis since the age of twelve- and I’m certainly much older than that now, made my parents practically livid with rage. It’s far too late now to change my misguided cannabis-fueled ways.

One of the things I learned from smoking cannabis is that it unlocks the creative side of my brain. I wouldn’t go so far as to say that cannabis made me an intellectual, that was already so… It just allowed me to think differently than my non-cannabis smoking peers.

When I recognize real thinkers, it’s usually through gatherings of other folks who do deep dives into their existence, usually with every puff of the finest cannabis in the world.

The Hall of Flowers is one such assemblage of like-minded heads. Aengus Cawley is one of the shining-star intellects that gathers with his peers in opening the minds and hearts of others through his ebullient smile. He truly has learned the secret and it unlocks the deep creativity that cannabis offers.

May I please introduce you to Aengus. He’s going to change the world, one perfectly curated cannabis experience at a time!

WB:  Please tell me what you’re working on right now? What are your six-month and twelve-month goals?

Aengus Cawley: We’ve put an extensive amount of time, effort, and R&D into launching BEED, and we’re thrilled to have come to market in such a holistic, 360-degree way. Every detail and nuance of the customer exploration, discovery, and acquisition phase has been meticulously thought through from end to end on our part.

We recently launched our DTC ecommerce site, continue to work with key retail partners like MedMen, The Artist Tree, Grassdoor, Green Qween, Double Eye, and now have our eyes set on further inserting BEED into the larger cultural narrative. We have participated in many cannabis-oriented events like Smoker’s Club, Hall of Flowers Palm Springs, and Napa’s BottleRock, and see our trajectory as a technology meets cannabis brand to continue to evolve and innovate in lockstep with our consumers’ preferences and needs.

We are already working on expanding the BEED Capsule line so we can grow with the ever-changing cannabis consumer to ensure brand longevity. We initially launched with six effect-based capsule offerings (ranging from a 1:1 THC / CBD blend to a hash-infused, 40%+ THC option) and are keen to add strain-based and flavor-focused options in the near future. Another avenue we’re actively exploring is retailer-specific and brand-specific BEED Capsule collaborations. There is so much brand loyalty amongst cannabis consumers nowadays, and it’s the logical next step to reach these untapped consumers via branding cross-pollination.

Growing and diversifying our retail partnerships over the next year is a big priority for us. With each new retailer comes seemingly infinite possibilities for collaboration and innovation. We are most excited and inspired by the unexpected and love the notion of BEED popping up in unusual settings and environments for ‘surprise and delight’ moments. Our end goal and hope through the simplicity of BEED are that we further destigmatize the plant by leveraging technology and in turn, help break through cultural divides and barriers. We want BEED to help bring cannabis to the masses.

WB: Please tell me about your company.  What is your technology?  What makes you unique?

Aengus Cawley: Inspired by the ease and accessibility of making a cup of coffee, BEED aims to elevate and streamline the cannabis experience by producing fresh, mess-free pre-rolls at the push of a simple, single button. BEED is the first capsule-based appliance for cannabis in the California market and allows consumers to enjoy the freshest, fastest, and most fun rolling experience, all in an environmentally friendly and economically conscious way.

The BEED Machine is the first and only fully-automated appliance to produce a single cannabis joint in 20 seconds. Our fully recyclable aluminum BEED Capsules are nitrogen sealed and contain .5g of premium cannabis that will stay fresh and maintain the full spectrum properties of the flower for up to one year.

We are stewards of the Earth and strive to help our consumers lead a more eco-conscious life. It’s part of our brand DNA. Each individual aluminum BEED capsule and the exterior packaging tube they are sold in are fully recyclable, and we’re constantly challenging ourselves to design and engineer novel ways to be more environmentally friendly.

From a pricing perspective, the BEED Machine and Capsule line surpasses the typical cannabis consumer’s expectations in all the right ways. Currently, the most affordable 0.5g California pre-rolls hover around the $5.50 mark. In contrast, our capsules are sold in 8-packs of single-serve 0.5g Capsules for $32, meaning that if you enjoyed one fresh BEED joint every day for an entire year, on average you would save over $500 based on this industry standard.

What’s more, you’ll enjoy a wholly consistent, fresh smoking experience each and every time with our capsule technology to reap all the benefits of the plant.

WB:  Do you prefer indoor to outdoor grown? Why? Terroir?

Aengus Cawley: I am personally (and likely as a result of my upbringing in rural Vermont) partial to outdoor, sun grown cannabis. There’s just something deeply special, even magical, about experiencing the plant in the most natural way. Unfortunately, it is not the most scalable option to provide consistent and fairly priced flower.

I’d be remiss not to acknowledge how indoor-grown cannabis has helped propel the industry into the $5.6B powerhouse it is today. It’s undeniable that indoor cultivation safeguards against external environmental elements and other hypothetical risks often out of growers’ control entirely. We at BEED have struck a happy balance between indoor and outdoor cannabis with the help of our partners at Glasshouse Farms. They believe the future of cannabis is greenhouse-driven, where high-quality, premium plants can be grown, nurtured, and cultivated using sustainably minded cultivation practices and in turn, sold at an accessible price point.

WB: Who is your mentor?

Aengus Cawley: It is less of a who has mentored me, and more of a what and where has inspired me.

First and foremost, I believe that physically disconnecting from society is essential to forming original (aka creative) thought. Getting out into nature and away from it all is the best way to ensure that your ideas are wholly your own. When you intentionally stop streaming, stop scrolling, and spend some time with just yourself, the universe tends to reward you with the clarity to create something unique and deeply impactful. Nature is a beautiful teacher.

My personal library is also a prized possession. Despite its physical weight and cumbersome nature, my library has been the perfect complement and often the driving factor of much of my personal and professional experience on this earth. Whether struggling through comprehending quantum physics by way of “The Dancing Wu Li Masters,” maximizing efficiency through pop culture phenomenon, Tim Ferris’s “4 Hour Work Week” or doubling down on the importance of having purpose beyond financials as I finish the inimitable Tony Hsieh’s “Delivering Happiness,” which was actually a recommendation from BEED’s CEO and a current mentor of mine, Ofer Kahana, literature has been a continual resource for further education.

WB: What is your passion?

Aengus Cawley: Making people smile. Bottom line. Whether it’s through art and approaching life from a uniquely creative lens, simple human interaction, or critical business decision making, bringing happiness to others is the most important thing to me at the end of the day. It’s actually what drew me initially to the cannabis industry and what ultimately led me to BEED.

First and foremost, cannabis is plant medicine and one that is essential to so many of the most important people in my life. The plant is so communal and it’s the shared experience of cannabis that brings people together in a positive way time and time again.

BEED’s technology helps democratize the plant in an approachable, lifestyle-centric way, and in turns helps further remove the cultural stigma of cannabis. When someone uses the BEED Machine for the first time, whether they were initially skeptical or are a cannabis veteran, consumers are always wowed by the simplicity of the process and are equally in awe when their freshly rolled joint is dispensed in a matter of seconds. … and after they take the first hit, well that’s when the real smiles set in.

Brand Photos: https://www.dropbox.com/sh/gl8h8o3itftf1mb/AAC1cRsosrg7kdqVhWBLw9oya?dl=0

Brand Video: https://youtu.be/XfUoDJ4wGiA

Aengus Photos: https://drive.google.com/drive/folders/1qE_NlfJTbSojOnstDjVvRgnfXcBKJMNe?usp=sharing

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Progress for Cannabis in Mississippi

Mississippi shook the entire cannabis industry when the state backslid on its initiative to bring cannabis to the state, though the vast majority of voters voted in favor of medical. I interviewed the founding member of the Mississippi Cannabis Trade Association in 2021 about that fiasco. Link here: https://www.skunkmagazine.com/mississippi-cannabis-legalization-goddamn/?v=7516fd43adaa.

Gratefully, On January 26, 2022, the Mississippi Legislature gave its final approval to the Mississippi Medical Cannabis Act (SB 2095), sponsored by Sen. Kevin Blackwell, to restore voters’ will by creating a medical cannabis program. Gov. Tate Reeves ® signed the bill into law on February 2, 2022 (mpp.org).

I caught up with Melvin C. Robinson III, who currently works as the Director of Communications and Media for the Mississippi Cannabis Trade Association, to get the scoop on the current state of cannabis in Mississippi.

Aja: What is the feel of the cannabis industry in Mississippi right now?

Melvin: Well, I can say from our perspective, we’re happy that we actually have a bill that is law now, so we can actually start up the program here. It was a long time coming. Fortunately, what happened with Initiative 65 is in the past now. We do have a bill. It’s not a perfect bill by far, but I truly believe that it’s a damn good start, especially considering other places in the south that have allowed medical programs to start. I think we have a great starting point. I think that this can really transform the state, especially with how agriculturally based our state is. I think that most people are just relieved that we actually have a program now.

Aja: What’s the bill called?

Melvin: The Mississippi Medical Cannabis Act.

Aja: You said it’s okay, but it’s not perfect. What would you change about this Act?

Melvin: I would definitely add more qualifying conditions. We have 22 right now, but I would add anxiety for sure. That’s not added. I would definitely want to see that. Patient access needs to be improved. Again, all of this is theory now. No one has had it in practice yet, but once we have it in practice, we’ll see more of the pros and the cons. Definitely those two things. I’m not speaking for MSCTA, but personally, I would allow home growth. There are some people who just wouldn’t be able to afford buying it as often as they would possibly need it. If people could grow or be allowed to grow it themselves, that would be good. It’s kind of weird because we are treating it as a medical item, but people also want to still treat it as a moral thing. They’re like, ‘Hey yeah, this is great. This will allow us to get people more relief from opioids and everything. Hey, but by the way, I don’t want that shit in my city.’ You know what I’m saying? For this program and for this industry to work, you don’t want to have this many obstacles preventing it from working. We want to make sure people can access pain management and things like that, but they also shouldn’t have to jump through hoops because you think everybody is trying to abuse this stuff.

Aja: You mentioned the environment of Mississippi and people making it a moral issue. I think a lot of people still see Mississippi as the Bible Belt and maybe a little bit ‘behind large cities.’

Melvin: Yeah. One thing you have to remember is the demographics of Mississippi. Mississippi is 38% black. Mississippi has the second blackest city in the nation, Jackson, Mississippi, at 83%. If you go back to that movie Django Unchained, one of the big plot points was Jamie Foxx saying, ‘Hey, I gotta go save my wife. She’s in Candyland in Mississippi.’ They cut to the scene in Mississippi, and you’re introduced to Mississippi with enslaved people walking through the mud with a slow scroll of ‘Mississippi’ going across the screen. I feel like people have that kind of thought about Mississippi because Mississippi needs a rebrand. We have a very special type of stubbornness, and a lot of the people are just stubborn about stuff. Because we have brain drain issues, we have population issues. For example, Mississippi was one of only three states to actually lose population during the pandemic. I think that our cannabis program is more progressive than others because of its free market approach. Take, for example, Florida has a certain amount of licenses. I think with Louisiana, don’t quote me. I’m not sure if this is correct, but I think they were allowing five licenses at a time. Here it is a free market approach where we don’t have any license caps or anything like that. You can apply for different types of businesses. You can have plant-touching businesses, you can have auxiliary businesses, and everything like that. One thing that I just don’t agree with is the taxation. It’s a 5% excise tax while the state doesn’t tax medical products or medicine. That’s one of those things where people are still trying to treat it like a moral issue instead of an actual medical issue. I think there also needs to be some social justice aspects around it, especially considering dispensaries. But as far as the licensing and the different prices to actually get into the program, it is not that bad. It’s just not. It’s really not.

Aja: Are you concerned that Mississippi will become a saturated market like Oklahoma since there is no cap in licensing?

Melvin: No, not at all. With Oklahoma, I believe it was what, $2,500. With Mississippi, we have different tiers. Say for cultivation, you have a micro cultivation tier, and then you have a cultivation tier. With a micro cultivation tier, you could have a less than 1000 square foot canopy area where you grow your product. It’s like probably $3,500 to set up. Versus a tier six cultivation facility, which is a hundred thousand square feet or more, which is thousands of dollars more. The thing is, if you have a thousand-foot cultivation facility, you’re not going to become a millionaire off that. If you have a 500-square-foot cultivation area, you’ll make a little money, and that’s great. People can participate, but it’s not one of these things where you have to have entire farms set up. I know Oklahoma had an issue with actually checking their businesses. With Mississippi, we have a seed-to-sell system that we’re going to have from the start. We have an entire department with the department of health that’s already hiring people. They’re already making sure they’re going to be able to examine and look at these businesses. Also, while the pricing of the industry to get in isn’t as high as in other places, there is sort of a barrier to entry. If you wanted to do a dispensary, for example, it’s not $2,500, but it’s not a million dollars liquid; it’s $40,000. All you have to do is pay your application fee and pay your licensing fee every year. The licensing fee will be yearly. It’s $25,000. That’s one of those things where $40,000 is not anything to sneeze at all, but it’s still not a million like other places.

Aja: What needs to be done to legalize homegrow?

Melvin: That kind of depends on zoning. If you were to do a home grow, it would count as a cultivation facility, and cultivation facilities are only allowed in agricultural and industrial zones. Now you can do it in a commercial zone, but you have to get a variance from your local zoning department, but no cultivation is allowed in residential areas. I think it’s really up to the legislature and just seeing what they come up with. We advocate for patient rights. The Mississippi Cannabis Trade Association we are a business organization first, but we hold advocacy education and community near and dear. We make sure we advocate for patients because people need this. People want an alternative form of healthcare. They might not want to take opioids. They might feel better using cannabis, and there’s nothing wrong with that. We just want to make sure that we have plenty of patients with plenty of access to it. One of the things that’s kind of shocking is during COVID, the big hospital here, University Medical Center, was giving out stats that said COVID hurts people with chronic illnesses or disabilities, and things like things like that. In a population of 3 million people, we have 900,000 people that covers. It’s one of those things where out of these 22 qualifying conditions, we have hundreds of thousands of people who can actually qualify for this Cannabis Act. That’s one of those things where we have to make sure they have adequate access to actually be able to reach a doctor who can give them their recommendation. We have to make sure we have enough dispensaries there. We have to make sure we have enough cultivators.

Aja: How bad is the opioid crisis in Mississippi right now?

Melvin: It’s definitely bad. If I am correct, I think Mississippi is like a top five area for opioid overdoses. Last year (2021), according to the Mississippi Department of Health, was the deadliest year for opioid overdoses that was ever recorded.

It’s one of those things where it’s like, where you’ll have people in positions of power saying, ‘Yeah, we’ve got to get people off these opioids. This cannabis sounds good. Hey, by the way, if you have a dispensary, let’s make sure you can’t have an access road.’ That didn’t happen, but you would hear some of these suggestions for the industry where it’s to the point of, ‘Hey, you’re not being serious. You are not being helpful. You sound insane.’ This is virtue signaling, basically.

It’s to the point where we will talk to people, and they will say their piece, and we will make sure to never talk to them again because I can’t take you seriously when you tell me, ‘Hey, we want to make sure dispensaries are 10,000 feet away from other things.’ You know what I’m saying? If you’re on the radio telling people that an ounce of cannabis is the size of a loaf of bread. One, you have no idea how big an ounce of something is. Two, it is so unserious that I just can’t take you seriously anymore.

Aja: How do you think legalization in Mississippi will impact the illicit market?

Melvin: Well, that depends on if people can actually access their medicine. If you have a county that is heavily populated or city that is heavily populated, we have a clause in the MLCA where cities and counties can actually opt out of the program. This is the thing. It doesn’t mean people can’t bring cannabis into your county or into your municipality. It doesn’t even mean they can’t use it or anything. It’s just saying, ‘We don’t want to have facilities, or we don’t want to have dispensaries or anything like that in this municipality.’ Over 800,000 people out of 1.3 million voters voted to bring medical cannabis to Mississippi. We try to make sure that we tell different people in leadership positions that ‘You want to go with the people on this one because you don’t want them to resent you.’ Unfortunately, we’ve had some bigger places opt out. We’ve had some countries opt out, and unfortunately, those people will have to go and find cannabis in different ways.

Aja: What does it say about the people of Mississippi that the vote was overwhelmingly, historically, ‘yes’?

Melvin: I think it says that people are ready for a little bit of change. I think people understand how silly some of this could be. I think people see it as medicine, and I think people see it as a way they can make a little bit of money here. Those are two things we definitely need in Mississippi. Oregon hasn’t blown up; you know what I’m saying? California hasn’t fallen off the face of the map because cannabis is legal. I think people recognize that. I think that’s why people wanted to buy in and make sure that we could access medical cannabis here.

Aja: I read an article that stated legalization in Mississippi will change the culture of the Southeast. What do you think about that statement?

Melvin: I could definitely see that. People are going to say, ‘Damn, we’re behind Mississippi.’ I think that’s one of those things that’s going to make a lot of other states like South Carolina, Tennessee, Texas, or Georgia say, ‘Hey, maybe we need to really consider this.’ Alabama, Louisiana, and Florida have pretty restrictive programs. Mississippi has the least restrictive one so far. I think it’s going to change the way those other places do their programs. I think that’s how that’s going to change the Southeast because, again, most of these states are poorer. Most of these states rely on federal aid. Mississippi, we rely on the most federal aid out of any state in the union. 40% of the money we get in this state is federal aid. I think it’s really something where we could change the shape of this entire area, the south and the Southeast, by making sure we buy into these programs.

Aja: What do you have to say to the people who are reading this article?

Melvin: I’m glad that we have a program now. I’m glad about the future of Mississippi…hold politicians accountable who said one thing and didn’t do that. Make sure you make your voice known and make your voice heard. I would also say if anybody needs any more information, I am very open. They can contact me at Melvin@mscta.org. They can contact the MSCTA, info@mscta.org. We’re willing to help anyone. We’re doing some signature drives now for places that have opted out. If you need any resources for that, we can most definitely send them. Yeah, I’m excited about the program. I’m excited about the industry. I’m excited about what the state will look like in five years.

The post Progress for Cannabis in Mississippi appeared first on SKUNK Magazine.



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Monday, 6 June 2022

Studies find CBD and other cannabinoids slow growth of colorectal cancer

Data from two recent studies suggests that cannabinoids including CBD, CBG and CBL can help stop the growth of colorectal cancer cells in humans, reports Forbes.

Colorectal cancer was the second most fatal type of cancer in the US in 2020, according to the US Centers for Disease Control and Prevention (CDC). It’s about a third as deadly as lung cancer. In terms of raw numbers, the American Cancer Society estimated 149,500 people were diagnosed in 2021. And colorectal cancer was responsible for nearly 52,000 deaths, per the CDC.

THC wasn’t included in either study. “But,” Lindsey Bartlett wrote for Forbes, “the studies do indicate that entourage effect with other cannabinoids like CBD, CBG, and CBL working in concert help to propel the ‘anti-proliferative’ effect. One of the studies even points to the entourage effect with cannabinoids and mushroom extracts working together to reduce the cancer cells.”

“The studies do indicate that entourage effect with other cannabinoids like CBD, CBG, and CBL working in concert help to propel the ‘anti-proliferative’ effect. One of the studies even points to the entourage effect with cannabinoids and mushroom extracts working together to reduce the cancer cells.”

— Lindsey Bartlett, for Forbes

In Product Trials, Cannabinoids Eliminate 90 Percent of Cancer Cells

Tests for a new product called Cannabotech Integrative-Colon found that a blend of cannabinoids and non-psychoactive mushrooms eliminated more than 90 percent of colon cancer cells in a cell model.

The study’s lead researchers, an oncologist and pharmacologist team, told Forbes that the key ingredients were CBD and several other minor cannabinoids. Specifics of the formula are proprietary, but results showed that the combined effect of the cannabinoids was significantly more effective than individual cannabinoids.

“Indeed, we have seen an interesting entourage effect not only when we have compared the single cannabinoids with the mixture, but also when we have included the mushroom extract with the cannabis extract,” oncologist Tami Peretz and pharmacologist Isaac Angel told Forbes.

The study also demonstrated that different cannabinoid affect subtypes of colon cancer differently, showing a potential value for personalized formulas.

Peretz and Angel said they deliberately excluded THC to avoid psychoactive effects in the medication. With results from the model study in hand, they’ll move on to in vivo studies in living organisms, then seek to publish their findings in a peer reviewed journal.

Research Study Finds CBD Slows Growth of Cancer Cells

A recent study by scientists at the University of Maryland’s Department of Nutrition and Food Science demonstrated that cannabidiol (CBD) has an anti-proliferative effect on human colorectal cancer cells.

The researchers wrote that CBD “has potential use in cancer treatment on the basis of many studies showing its anti-cancer activity in diverse types of cancer, including colon cancer.

“However,” they continued, “its mechanism of action is not yet fully understood.”

The researchers found three underlying mechanisms: CBD represses viability of human colorectal cancer cells; stops the cell cycle; and increases the death of colorectal cancer cells.

It does this via the cannabinoid type 2 receptor — the receptor more strongly associated with nonintoxicating cannabinoids.

“Our data indicate that CBD and its derivatives could be promising agents for the prevention of human colorectal cancer,” the study’s authors concluded.

Treatment May Be Coming Soon

The results of these studies offer hope for those who hope cannabinoids can one day be used to help treat colorectal and other types of cancer.

They might not have to wait long. Cannabotech expects to launch its Integrative-Colon treatment in the US, the UK and Israel later this year.


from Nothing But Hemp https://www.nothingbuthemp.net/post/studies-find-cbd-and-other-cannabinoids-slow-growth-of-colorectal-cancer

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